D3 - Vitamin D

Benefits:

• Keep the immune system in check
• Build and Maintain Strong Bones and teeth
• Enhance Muscle growth & Strength

DESCRIPTION:
Cholecalciferol (Vitamin D3) is the active form of vitamin D. Vitamin D is essential for normal bone growth, development and to Maintain bone density. Stimulates calcium and phosphate absorption from small intestine; stimulates phosphate resorption in renal tubules; stimulates secretion of calcium into blood from bone.

DOSAGE:
Take 1 softgel daily with meal or as directed by a healthcare professional. Do not exceed the recommended daily dose.

PRECAUTIONS:
Store below 30°C. Refrigeration recommended in hot climates. Patients suffering from renal diseases should use under medical supervision. Keep out of the reach of children.

COMPOSITION:

Each soft gel capsule contains:
Vitamin D3 BP...... 10,000IU

INDICATIONS:
1. As dietary supplement for prevention of Vitamin D deficiency in adults and children.
2. Prevention of Vitamin D deficiency in high risk patients with malabsorption, certain chronic diseases, disorders of metabolism, drugs or other causes.
3. Treatment of vitamin D deficiency states like rickets, osteomalacia and osteoporosis. In all cases calcium supplements must be provided along with Vitamin D supplementation.

CONTRAINDICATIONS:
D3 may not be used in the following conditions:
Hypersensitivity to Cholecalciferol or any of the ingredients of the drug.
• Hypercalcemia and/or hypercalciuria.
D3 should not be administered to patients with a tendency towards the formation of kidney stones containing calcium with pseudohypoparathyroidism

CAUTIONS:
D3 should be administered only with caution:

• To patients with a disturbed renal calcium and phosphate excretion.
• To patients taking anticonvulsants.

To immobilized patients, e.g. by cast, (risk of the hypercalcemia, hypercalciuria).
.To Suffering from sarcoidosis since the risk of transformation of vitamin D into its active metabolites is increased. The calcium levels in plasma and urine should be supervised at these patients.
During long term therapy the calcium levels in the serum and in the urine should be supervised, and the kidney function should be checked by measuring the serum creatinine every 3 to 6 months. This check is particularly important for older patients and for patients taking cardiac glycosides or diuretics. In the case of hypercalcemia or reduced kidney function the dosage must be reduced or the therapy discontinued. It is advisable to discontinue the therapy if the calcium level in the blood exceeds 105mg/ml or if calciuria is >4 mg/kg/day in adults or 4-6 mg/kg/day in children.

PREGNANCY & LACTATION:
There is no evidence to suggest that vitamin D is teratogenic in humans even at very high doses. Cholecalciferol should be used
during pregnancy only if the benefits outweigh the potential risk to the fetus. It should be assumed that exogenous Cholecalciferol passes into the breast milk. In view of the potential for hypercalcaemia in the mother and for adverse reactions from Cholecalciferol in nursing infants, mothers may breastfeed while taking Cholecalciferol, provided that the serum calcium levels of the mother and infant are monitored.

ADVERSE EFFECTS:
The side effects of vitamin D result as consequence of the hypercalcemia. Hypercalcemia can appear depending on dosage and duration of therapy with its acute symptoms (arrhythmias, nausea, vomiting, psychic symptoms, and impaired consciousnesses) and chronic symptoms (polyuria, polydipsia, weight loss, kidney stone formation, nephrocalcinosis, extraosseous calcifications).

PRESENTATION:
D3 Soft Gel Capsule 10,000 IU: Pack of 2 x 10 capsules.